DOI: 10.21276/ajptr
Fri, 21 Jun 2019

Approaches for improvement of vesicular system-Pro-vesicular drug delivery

Gangadhar Veerapu1, Gangadharappa.HV1*, B Nagashubha1

1.Department of Pharmaceutics, JSS College of Pharmacy, JSS University, Mysore-570015, India.


Drug delivery systems using colloidal particulate carriers such as liposomes and niosomes have distinct advantages over conventional dosage forms. This class of drug carrier systems will likely play an increasingly important role in drug delivery. However, there remain significant problems like instability in the general application of liposomes and niosomes for drug delivery. Pro vesicular drug delivery developed to overcome the stability problems associated with vesicular drug delivery systems composed of water soluble porous powder as a carrier drug is dissolved in an organic solvent to produce free-flowing granular product. To overcome the limitations (especially chemical and physical stability) of vesicular drug delivery systems like liposomes, niosomes, trans-ferosomes, and pharmacosomes, the pro-vesicular approach was introduced. The present article gives a brief overview of introduction on proliposomes, Pro-niosomes, Dry granular liposomes, mixed micellar proliposomes, Pro-transferosomes and its applications.

Keywords: Proliposomes, Pro-niosomes, Pro-transferosomes, Dry granular liposomes.



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