Mon, 18 Dec 2017

Review on Nasal Microspheres

Digambar Yashawant Mali*, Swati Gokul Talele, Rajendra Mogal, Ghanashyam Chaudhari

1.Sandip Institute of Pharmaceutical Sciences, Mahiravani, Nasik, Maharashtra, India.


ABSTRACT

Microsphere is a carrier system for delivery of therapeutic candidate. Nasal microspheres offers significant advantages over other type of drug delivery system. It modulates absorption characteristics of the drug by enhancing drug residence time in the nasal cavity and subsequently may increase bioavailability profile of administered drug. Prior to formulation some physicochemical properties of drug are need to be considered like molecular weight, solubility, pKa and partition coefficient of drug etc. Till date various methods have been adopted for fabrication of nasal microspheres are like spray drying, emulsion crosslinking, Solvent Evaporation etc. Obtained microspheres can characterized for various properties like its morphology, drug content, and zeta potential etc. Present  review mainly focuses on overview of microsphere technology for nasal administration of drug.

Keywords: Microspheres, Nasal, Mucociliary Clearance


[PDF]  Viewed: 1265  Downloaded: 158
  • Call for paper

    American Journal of PharmTech Research (AJPTR) is a peer-reviewed, bimonthly official international journal allowing access to abstracts and full-text.

    Read more...

     

  • Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.

    Read more...

  • Article Statastics

    American Journal of PharmTech Research (AJPTR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission

    American Journal of PharmTech Research (AJPTR) is one of the International open access journal devoted to various disciplines in science and technology.

    Read more...

web counter
web counter