Mon, 18 Dec 2017

Polymer Based Microgels/Nanogels: Development and Application In Drug Delivery

Ganga Srinivas1*, Pooja Ramnathkar1

1.Department of Pharmaceutics, Vivekanand Education Society’s College of Pharmacy, Chembur, Mumbai – 400078


ABSTRACT

Microgels/nanogels are crosslinked polymeric particles, which can be considered as hydrogels if they are composed of water soluble/swellable polymer chains. These polymeric particles possess high water content, biocompatibility, and desirable mechanical properties. Offers unique advantages for polymer-based drug delivery systems (DDS) such as a tunable size from nanometers to micrometers, a large surface area for multivalent bioconjugation, and an interior network for the incorporation of biomolecules. This review article describes the recent developments of microgel/nanogel particles as drug delivery carriers for biological and biomedical applications and also various synthetic strategies for the preparation of microgels/nanogels.

Keywords: Microgels, nanogels, polymers based drug delivery systems.


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