Mon, 18 Dec 2017

Phytochemical, Antioxidant and Antiinflammatory studies on the leaves of Putranjiva roxburghii

P. L. Rajagopal*1, S. S. Kiron1, K. R. Sreejith2, S. Aneeshia3

1.Asst.Prof.,Department of Pharmacy Practice, Academy of Pharmaceutical Sciences, Pariyaram Medical College, Kannur, Kerala, .India.

2.Asst.Prof,  Department of Pharmaceutical Chemistry, Academy of Pharmaceutical Sciences, Pariyaram Medical College, Kannur, Kerala,.India.

3.Lecturer, Department of Medical Laboratory Technology, Academy of Paramedical Sciences, Pariyaram Medical College, Kerala, India.


ABSTRACT

The In-vitro antioxidant and anti-inflammatory activity of the leaf extract of Putranjiva roxburghii were studied along with preliminary phytochemical investigation. The leaf of the plant contains mainly anthracene, cardiac and flavonoid glycosides along with phenolic compounds. Since many flavonoids have remarkable anti inflammatory activity the present work aims at evaluating the anti inflammatory activity of Putranjiva roxburghii by HRBC membrane stabilization. The ethanolic extract of the leaf was anlysed for antioxidant activity by DPPH method at different concentrations. Throughout the studies leaf extract showed potent antioxidant activity. The antioxidant activity was found to be concentration dependent and may be attributed to the presence of high flavonoid content in the leaves of Putranjiva roxburghii

Key Words: Anti oxidant activity, Anti-inflammatory, Putranjiva roxburghii, HRBC Membrane stabilization, DPPH


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