Mon, 18 Dec 2017

Visible Spectrophotometric Method for Estimation of Lurasidone Hydrochloride In Synthetic Mixture

Satish A Patel1, Krunal Y Patel1*.

1. Department of Pharmaceutical Quality Assurance, Shree S. K. Patel College of Pharmaceutical Education & Research, Ganpat University, Kherva – 382711, Mehsana, Gujarat, India.


ABSTRACT

A simple, sensitive, accurate, precise and economical visible spectrophotometric method was developed and validated for the estimation of lurasidone Hydrochloride in synthetic mixture. The method is based on the reaction of lurasidone Hydrochloride with bromocresol green dye in dichloromethane giving yellow color chromogen, which shows maximum absorbance at 418 nm against reagent blank. The chromogen obeyed Beer’s law in the concentration range of 4-12 µg/ml for lurasidone Hydrochloride. The results of the analysis have been validated statistically and by recovery studies.

Keywords: Lurasidone Hydrochloride, Chromogen, Bromocresol green, Visible spectrophotometric.


[PDF]  Viewed: 953  Downloaded: 111
  • Call for paper

    American Journal of PharmTech Research (AJPTR) is a peer-reviewed, bimonthly official international journal allowing access to abstracts and full-text.

    Read more...

     

  • Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.

    Read more...

  • Article Statastics

    American Journal of PharmTech Research (AJPTR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission

    American Journal of PharmTech Research (AJPTR) is one of the International open access journal devoted to various disciplines in science and technology.

    Read more...

web counter
web counter