DOI: 10.21276/ajptr
Fri, 21 Jun 2019

H2O-Mediated Efficient Tandem Synthesis of Barbituryl Thiocarbamides using Amberlyst-15 As A Heterogeneous Solid Catalyst

Atul A. Jichkar1, Madhuri M. Sontakke2, Chandrakant S. Bhaskar3, Madhukar G. Dhonde*1, Baliram N. Berad2

1.Department of Chemistry, Shri Mathuradas Mohota college of Science, Nagpur(MS), India

2.Department of Chemistry, RTM, Nagpur University, Nagpur(MS), India – 440033.

3.Department of Chemistry, Art’s, Commerce & Science College, Koradi (MS), India


H2O-mediated efficient, tandem synthesis of barbituryl thiocarbamides by the nucleophilic addition reaction of uramil and aryl isothiocyanates using Amberlyst-15 as a heterogeneous solid catalyst is being reported. The novel and clean methodology offers the advantages that includes short reaction time, good yields, and operational simplicity, less leaks, environmentally benign procedure apart from recyclable, reusable catalyst.

Keywords; Thiocarbamides, green synthesis, Amberlyst-15.

[PDF]   Viewed: 1031   Downloaded: 102
  • Call for paper

    American Journal of PharmTech Research (AJPTR) is a peer-reviewed, bimonthly official international journal allowing access to abstracts and full-text.



  • Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.


  • Article Statastics

    American Journal of PharmTech Research (AJPTR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission

    American Journal of PharmTech Research (AJPTR) is one of the International open access journal devoted to various disciplines in science and technology.


web counter
web counter