DOI: 10.21276/ajptr
Fri, 19 Apr 2019

Investigation of Flavones as Efficient anti–oxidant and anti-inflammatory Agents

Rajashree A. Markandewar*1, M. H.Ghante2, M. A. Baseer3.

1Department of Applied Chemistry, Ballarpur Institute of Technology, Ballarpur-442701.

2Department of Pharmacognosy, Nanded Pharmacy College, Nanded-431601

3Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-431601


Flavones, have been synthesized by the oxidative cyclization of 2'-hydroxychalcones using catalytic amount of iodine in presence of dimethyl sulfoxide (DMSO) in maximum yield. The synthesized compounds were evaluated for anti-oxidant and anti-inflammatory potential. Two compounds showed good anti-inflammatory activity as compared to their antioxidant activities. The synthesized compounds were characterized by IR, 1HNMR and MS Spectroscopy.

Keywords: Flavones, anti-oxidant, anti-inflammatory, oxidative-cyclization, DMSO.

[PDF]   Viewed: 952   Downloaded: 105
  • Call for paper

    American Journal of PharmTech Research (AJPTR) is a peer-reviewed, bimonthly official international journal allowing access to abstracts and full-text.



  • Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.


  • Article Statastics

    American Journal of PharmTech Research (AJPTR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission

    American Journal of PharmTech Research (AJPTR) is one of the International open access journal devoted to various disciplines in science and technology.


web counter
web counter