Mon, 18 Dec 2017

Formulation and Evaluation of Bilayered Tablets of Anti-Platelet Drugs

Krishna R. Raparla1, YA Chowdary*2  Sushma P1

1.Department of  Pharmaceutics, Vaageswari Institute of Pharmaceutical Sciences, Beside LMD police station, Karimnagar, Andhrapradesh, India – 505481

2.Department of  Pharmaceutics, NRI College Of Pharmacy, Pothavarapadu village, Via Nunna, Agiripalli Mandal, Krishna Dist, Andhrapradesh, India – 521 212


ABSTRACT

A series of chalcones was synthesized by the Claisen-Schmidt condensation and the structures of 1-(4-bromophenyl)-3-phenylprop-2-en-1-ones were established with the help of IR and NMR study, then their effect was observed on bovine serum albumin. We have found that the synthesized chalcones interacted with bovine serum albumin irrespective of position and nature of substituent. 1-(4-bromophenyl)-3-(3-methoxyphenyl)-prop-2-en-1-one has been found to interact with BSA maximally.

Keywords: Bovine serum albumin, interaction studies, chalcones of p-bromoacetophenone.


[PDF]  Viewed: 700  Downloaded: 106
  • Call for paper

    American Journal of PharmTech Research (AJPTR) is a peer-reviewed, bimonthly official international journal allowing access to abstracts and full-text.

    Read more...

     

  • Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.

    Read more...

  • Article Statastics

    American Journal of PharmTech Research (AJPTR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission

    American Journal of PharmTech Research (AJPTR) is one of the International open access journal devoted to various disciplines in science and technology.

    Read more...

web counter
web counter