Mon, 18 Dec 2017

Effect of the probiotic yeast Saccharomyces boulardii on Giardia lamblia and electrolyte ratio in mice.

Sabaa Tahir Mohamed1*, Hamzia Ali Ajah1

1.Department of Biology, College of Science, Mustansiryia University, Baghdad, Iraq


ABSTRACT

The principal objective for our study was to evaluate the efficacy of Saccharomyces boulardii against Giardia  lamblia infection and investigated  the mechanism of this anti diarrheal effect on electrolyte (sodium,potassium and chloride) changes compared with metronidazole by using mice models.A single oral dose of S.boulardii of up to 5 x106cfu/0.1 of viable cells reduced parasite appear in feces and disappear completely at the 7th day compared with metronidazole the cysts parasite continued till 8th day. The yeast also caused increased potassium and sodium while decrease chloride level in serum. The histo morphological study findings showed in the group which was given S. boulardii the majority of intestinal villi return to normal shape. These finding indicated  that S.boulardii may be effective  in treating giardiasis also  has specific  effects on electrolyte  secretary  response.

Keywords: Saccharomyces boulardii ; Giardia lamblia ; probiotic

 


[PDF]  Viewed: 1418  Downloaded: 134
  • Call for paper

    American Journal of PharmTech Research (AJPTR) is a peer-reviewed, bimonthly official international journal allowing access to abstracts and full-text.

    Read more...

     

  • Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.

    Read more...

  • Article Statastics

    American Journal of PharmTech Research (AJPTR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission

    American Journal of PharmTech Research (AJPTR) is one of the International open access journal devoted to various disciplines in science and technology.

    Read more...

web counter
web counter