Thu, 14 Dec 2017

A REVIEW ON PHARMACEUTICAL APPLICATIONS OF LIQUISOLID TECHNIQUE

Narender Thakur1, Sukhbir Lal Khokra1, Dharmesh Sharma1, Naseeb Singh Thakur1, Rahul Purohit1, Vikrant Arya2*

 

1. Department of Pharmaceutical Sciences, Manav Bharti University, Solan, H.P., India

2*. Department of Pharmacognosy, Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial College of Pharmacy, Bela, Ropar, Punjab, India


ABSTRACT

The term “liquisolid medication” implies oily liquid drugs and solutions or suspensions of water insoluble drugs carried in suitable non-volatile solvent systems. Liquisolid compacts demonstrated a considerably higher drug dissolution rates than those of conventionally made capsules and directly compressed tablets. This was due to the increased wetting properties and surface of drug available for dissolution. This review paper highlights the application of liquisolid technique to enhance the solubility and dissolution of water insoluble drugs. This technique is appropriate for poorly or water insoluble drugs and also for immediate or sustained release formulations. This review also depicts the various formulation parameters that must be optimized before formulation the liquisolid compacts.

Keywords: Liquisolid technique; Solubility; Dissolution; Poorly; Water insoluble drugs


[PDF]  Viewed: 2564  Downloaded: 934
  • Call for paper

    American Journal of PharmTech Research (AJPTR) is a peer-reviewed, bimonthly official international journal allowing access to abstracts and full-text.

    Read more...

     

  • Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.

    Read more...

  • Article Statastics

    American Journal of PharmTech Research (AJPTR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission

    American Journal of PharmTech Research (AJPTR) is one of the International open access journal devoted to various disciplines in science and technology.

    Read more...

web counter
web counter