Tue, 21 Nov 2017

Comparative Characterization of Phytomedicinal Constituents of Xylopia Aethiopica.

 

Nworah Doris Chinwe*1, Nwafor Arthur1, Bekinbo Mpakaboari Tonye1

 

1. Department of Human Physiology,Faculty of Basic Medical Sciences,College of  Health Sciences,University of Port Harcourt, ,Rivers State,P.M.B. 5323, Choba Nigeria.


 

ABSTRACT

Preliminary characterization and isolation of phytomedicinal components of dried black fruits of xylopia aethiopica in hydro-methanolic (1:4 v/v), hydro-ethanolic (1:4, v/v), methanolic, ethanolic and aqueous solvents has been compared. Results showed variability and significant differences in phytomedicinal compositions and the potency ranked: hydro-methanolic > hydro-ethanolic > methanolic > ethanolic = aqueous and the percentage difference was 75%, 54%, 45.8%, 29% =29% which perhaps validates the efficacy of the therapeutic potentials of xylopia aethiopica for many of the traditional medicinal applications.  Anthraquinone and combined anthraquinone were exclusively found in hydro-methanolic and methanolic concentrates and accounted for 44.4 % and 33.3 % respectively. Glycosides (-terpene, sterols and deoxy-sugar) accounted for 100% in hydro-alcoholic concentrates respectively. Alkaloids and the phenolic compounds flavonoids and tannins with the exception of saponins which was negligible or absence in the solvents were also the phytomedicinial constituents. Results suggest that the ability of hydro-alcoholic to enhance the isolation of useful constituents might be attributed to the differential solubility of the combined hydrophobic and hydrophilic components of the phytomedicinal bioactive ingredients in the solvent which, is still subject to further studies. Hydro-alcoholic, specifically hydro-methanolic, therefore is recommended for isolation and characterization of economically important medicinal plants of medical interest.

Keywords: Xylopia aethiopica, hydro-ethanolic, hydro-methanolic, differential solubility anthraquinone, combined anthraquinone, medicinal plant.


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