Mon, 20 Nov 2017

Evaluation of In-Vitro Antioxidant and Anti-inflammatory Activities of extract of Ocimum Sanctum linn

 

T. Satapathy1, B. Meher1*, S. Roy1, J. Parida1, S. P. Tiwari1, B. Tripathy2

1. Columbia Institute of Pharmacy , Tekari , Raipur , CG-493 111

2. University Department of Pharmaceutical Sciences , U. U. , BBSR- 751004


 

ABSTRACT

 

The objective of the study was to investigate the anti-oxidant and anti-inflammatory effect of aqueous extract of Ocimum sanctum leaf. The antioxidant and anti-inflammatory activities were evaluated using in vitro Ferric reducing power, Free radical scavenging activity by DPPH  method, hydroxyl radical scavenging activity, Nitric oxide radical scavenging activity, Hyaluronidase inhibition assay. The effect was compared with a known antioxidant agent (BHA/Ascorbic acid). It was found that the extract at different concentration exhibited significant dose dependent antioxidant and anti-inflammatory effect

Key words: Ocimum sanctum, Free radical, DPPH, Hyaluronidase inhibition


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