DOI: 10.21276/ajptr
Mon, 25 Mar 2019

A Review on Alzheimer’s Disease: Pathogenesis and Management


Bibekananda Meher1*, Deepak Kumar. Dash2, Rajib Lochan Maharana3, Sumi Jose1

1.Columbia Institute of Pharmacy Raipur, C G-493111

2.Royal College of Pharmacy Sciences, Raipur, CG-492099

3.Roland Institute of Pharmaceutical Sciences, Berhampur, Odisha- 760010



Alzheimer’s disease is the most prevalent form of dementia. Neuropathogenesis is proposed to be a result of the accumulation of amyloid β- peptides in the brain together with oxidative stress mechanisms and neuroinflammation. Drugs effective in Alzheimer’s disease (AD) should have several aims: to improve the cognitive impairment, control the behavioral and neurological symptoms, delay the progression of the disease, and prevent the onset. This review discusses the molecular mechanism of Alzheimer’s disease with a focus on the different agents those are inhibit the progression of the disease and improved patients condition and status..

Key words: Alzheimer’s disease, β-amyloid, Tacrine, Rivastigmine

[PDF]   Viewed: 1544   Downloaded: 183
  • Call for paper

    American Journal of PharmTech Research (AJPTR) is a peer-reviewed, bimonthly official international journal allowing access to abstracts and full-text.



  • Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.


  • Article Statastics

    American Journal of PharmTech Research (AJPTR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission

    American Journal of PharmTech Research (AJPTR) is one of the International open access journal devoted to various disciplines in science and technology.


web counter
web counter