DOI: 10.21276/ajptr
Mon, 25 Mar 2019

Design and Synthesis of Some Pyrazole, Isoxazole, Benzoxazepine and Benzothiazepine Derivatives as Anti-Inflammatory and Antimicrobial Agents


Babasaheb V. Kendre1, Mahadev G. Landage1, Sudhakar R. Bhusare*1

1.Division of Organic Chemistry, Dnyanopasak College, Parbhani, MS, India



An efficient and rapid synthesis of some new pyrazoles, isoxazole, benzoxazepine and benzothiazepine derivatives is described. The synthesized compounds were investigated for their anti-inflammatory and antimicrobial activities and some of them showed potent anti-inflammatory and anti-microbial activities.

Keywords: Anti-inflammatory activity, Prostaglandin, Pyrazole, Isoxazole, Benzoxazepine, Benzothiazepine, Antimicrobial activity

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