Tue, 21 Nov 2017

EVALUATION OF WOUND HEALING ACTIVITY OF AEGELE MARMELOS LEAVES IN MALE ALBINO RATS

Renu Solanki1*, Vipin Mathur1, Manoj Mathur2, Shiv Kumar Purohit2

 

1. Lachoo Memorial College of Science and Technology, Pharmacy Wing, Jodhpur, Rajasthan, India.

2. College of Veterinary and Animal Science, Rajasthan Agricultural University, Rajasthan, India.


ABSTRACT

 

Wounds are major cause of physical disabilities. Wound healing consists of orderly progression of series of events that establish the integrity of the damaged tissues. Aegele marmelos (Bael) is used for medicinal purposes, including treatment of dyspepsia, inflammation, asthma, hypoglycemia, cancer, hepatitis, diabetes, sinusitis, tuberculosis, diarrhea, dysentery, as astringent, digestive, stomachic etc. The present study was undertaken on ethanolic extract of leaves of Aegele marmelos on wound healing activity through topical route on excision wound model. The activity was compared with standard drug Povidone Iodine ointment (5% w/w). The leaves of  Aegele marmelos ethanolic extract was found to have better and faster rate of wound healing effect than Povidone iodine ointment on excision wound model.

Key Words: Aegele marmelos, povidone iodine ointment, wound healing activity, excision wound model.


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