Sun, 17 Dec 2017

An Update on Taste Masking Technologies for Orodispersible Tablets

Snehalatha*1, Shivakumar B2, Santoshvarma PR1.

 

 

1. PG Department of Pharmaceutics, SJM College of Pharmacy, Chitradurga-577502, Karnataka, India.

2. PG Department of Pharmaceutical Chemistry, BLDEA’S college of Pharmacy, Bijapur, Karnataka, India.


ABSTRACT

 

ODTS are solid unit dosage form which dissolve or disintegrate rapidly in mouth without water. So, acceptability of this dosage form mainly depends on its taste i.e. mouth feel. So it becomes necessary to develop such an ODT for that must be acceptable in taste to patient many techniques are available to mask the taste of drugs. These techniques not only serve as to mask the taste of drug but also to enhance the bioavailability of drug. Taste masking technology involves the development of a system that prevents the active substance interacting with the taste buds, thereby eliminating or reducing the bitter taste. This review describes the commonly used techniques that are adopted for masking the taste of bitter drugs and dosage form palatable. The common methods include addition of sweeteners, coating of drugs adjusting the pH values, granulation, freeze drying, forming complex with ion exchange resins etc.

Key words: orodispersible tablets (ODTs), taste masking.

 


[PDF]  Viewed: 1482  Downloaded: 273
  • Call for paper

    American Journal of PharmTech Research (AJPTR) is a peer-reviewed, bimonthly official international journal allowing access to abstracts and full-text.

    Read more...

     

  • Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.

    Read more...

  • Article Statastics

    American Journal of PharmTech Research (AJPTR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission

    American Journal of PharmTech Research (AJPTR) is one of the International open access journal devoted to various disciplines in science and technology.

    Read more...

web counter
web counter