DOI: 10.21276/ajptr
Thu, 20 Jun 2019

Anencephaly: A Neural Tube Defect A Review

Priya Gupta1*, Parminder Nain1, Jagjit Singh2


1. M.M College of Pharmacy, Maharishi Markandeshwar University, mullana, Ambala (Haryana).

2. Amity Institute of Pharmacy, Amity University, Noida, Uttar Pradesh..


Neural tube defects (NTDs) are one of the commonest birth defects. They form a spectrum of disease ranging from anencephaly to spina bifida occulta. Anencephaly is a cephalic disorder that occurs when the cephalic (head) end of the neural tube fails to close, resulting in the absence of a major portion of the brain, skull, and scalp. However few studies have systematically looked into the etiopathogenesis of anencephaly which mainly includes nutritional deficiencies and genetic predisposition. Efforts are a foot for universal food fortification with folic acid in the hope of preventing NTDs. So we hereby conclude that caution should be exercised before widespread of anencephaly or the NTDs.

Keywords: Neural tube defect, Anencephaly

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