DOI: 10.21276/ajptr
Fri, 19 Apr 2019

Comparative Tableting Properties of Three Local Potato Starches III: The Disintegrant Properties


J. Muazu1*, H. Musa2, A. B. Isah2, P. G. Bhatia2


1. University of Maiduguri, Nigeria

2. Ahmadu Bello University, Zaria, Nigeria



This study aimed at comparing the disintegrant properties of three potato starches with Maize starch BP as well as effect of method of incorporation of disintegrant on release of paracetamol tablet formulation. The disintegrant property was assessed by both disintegration and dissolution times of the formulation. The results showed that tablets produced with potato starch were similar in disintegration and dissolution times with those formulated with Maize starch BP. Disintegrants employed extra-granularly showed better disintegration than intra-granular or intra-extra-granular. Therefore the potato starches can be used as a disintegrant in paracetamol tablets formulation

Keywords: disintegrants, potato starch, formulation, dissolution time, incorporation

[PDF]   Viewed: 1764   Downloaded: 131
  • Call for paper

    American Journal of PharmTech Research (AJPTR) is a peer-reviewed, bimonthly official international journal allowing access to abstracts and full-text.



  • Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.


  • Article Statastics

    American Journal of PharmTech Research (AJPTR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission

    American Journal of PharmTech Research (AJPTR) is one of the International open access journal devoted to various disciplines in science and technology.


web counter
web counter