Sun, 17 Dec 2017

A Review - Bilayer Floating Drug Delivery System

 

Pankaj P. Ostwal1*, V.N.Shrikhande1, N.M.Mahajan1, Yogesh L. Jadhav2, Mayur S. Jain3, Sumit P. Jain3

 

1.      I. B. S. S. College Of Pharmacy, Malkapur Dist. Buldhana.

2.      Manav Bharti University, Solan (H.P)

3.     Tapi Valy College of Pharmacy, Faizpur, Dist. Jalgaon.


 

ABSTRACT

In the recent years, scientific and technological advancements have been made in the research and development of novel drug delivery systems by overcoming physiological troubles such as short gastric residence times and unpredictable gastric emptying times. Several approaches are currently utilized in the prolongation of the gastric residence times, including floating drug delivery systems, swelling and expanding systems, polymeric bioadhesive systems, modified-shape systems, high-density systems and other delayed gastric emptying devices. This review entitled the detailed scenario related to Bilayer floating drug delivery system with their advantages over the conventional drug delivery system and also limitation, which are helpful in development of dosages form. Various types of techniques employed for development of this dosages form. Review focused on formulation aspect of effervescent floating drug delivery system with their evaluation techniques. The purpose of this comprehensive review is to compile the work going on this delivery system. Which provide the valuable information related to formulation aspect to achieve gastric retention and discussed the various factors affect and to overcome it

Keywords: Gastric residence time, Floating drug delivery system, Effervescent, Non-effervescent.

 


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