DOI: 10.21276/ajptr
Thu, 20 Jun 2019

A Review - Bilayer Floating Drug Delivery System


Pankaj P. Ostwal1*, V.N.Shrikhande1, N.M.Mahajan1, Yogesh L. Jadhav2, Mayur S. Jain3, Sumit P. Jain3


1.      I. B. S. S. College Of Pharmacy, Malkapur Dist. Buldhana.

2.      Manav Bharti University, Solan (H.P)

3.     Tapi Valy College of Pharmacy, Faizpur, Dist. Jalgaon.



In the recent years, scientific and technological advancements have been made in the research and development of novel drug delivery systems by overcoming physiological troubles such as short gastric residence times and unpredictable gastric emptying times. Several approaches are currently utilized in the prolongation of the gastric residence times, including floating drug delivery systems, swelling and expanding systems, polymeric bioadhesive systems, modified-shape systems, high-density systems and other delayed gastric emptying devices. This review entitled the detailed scenario related to Bilayer floating drug delivery system with their advantages over the conventional drug delivery system and also limitation, which are helpful in development of dosages form. Various types of techniques employed for development of this dosages form. Review focused on formulation aspect of effervescent floating drug delivery system with their evaluation techniques. The purpose of this comprehensive review is to compile the work going on this delivery system. Which provide the valuable information related to formulation aspect to achieve gastric retention and discussed the various factors affect and to overcome it

Keywords: Gastric residence time, Floating drug delivery system, Effervescent, Non-effervescent.


[PDF]   Viewed: 2292   Downloaded: 402
  • Call for paper

    American Journal of PharmTech Research (AJPTR) is a peer-reviewed, bimonthly official international journal allowing access to abstracts and full-text.



  • Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.


  • Article Statastics

    American Journal of PharmTech Research (AJPTR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission

    American Journal of PharmTech Research (AJPTR) is one of the International open access journal devoted to various disciplines in science and technology.


web counter
web counter