Sat, 18 Nov 2017

Formulation and Evaluation of Herbal Gel Contains the Flower Extract of Butea monosperma

 

B.H. More1*, S.N. Sakharwade2, D.M. Sakarkar1

1. Sudhakarrao Naik Institute of Pharmacy, Nagpur road, Pusad Dist: Yavatmal 445104 (M.S) India.

2. L.A.D. and SMT R.P. College for Women, Dept. of Cosmetic Technology, Seminary Hills, Nagpur.


 

ABSTRACT

There is a growing demand for herbal cosmetics in the world market and they are invaluable gifts of nature. Therefore, the basic intention of the present study was to design a proper formulation contain the flower extract of Butea monosperma (FEBM) with improved physical parameter. To accomplish this intention the herbal gel was prepared and subjected to evaluation of the various parameters. The cosmetic gel formulation was designed by using ethanolic extract of FEBM in varied concentration (0.5, 1 and 1.5%) using carbapol 940 as gelling agent and evaluated for various parameters. The study was also undertaken to evaluate the stability of gels. The prepared gels were evaluated for various physicochemical parameters such as physical observation, homogeneity, pH determination, viscosity, spreadability, extrudability, drug content, rate of drug permeability, stability as per ICH guidelines and HPTLC fingerprint profiles. All developed gels showed good homogeneity with absence of lumps. All gels were found to be stable with respective to their pH, viscosity and drug content. The extrudability and spreadability were also found to be less variant after stability study. The gels of Butea monosperma are radically permeable from skin of rats as demonstrate by the in-vitro permeation study. However, further preclinical studies of gel need to evaluate further confirming the reported biological activities. There is also need to evaluate effects especially in human phase, would be beneficial to assess its usefulness more exactly.

Keywords: Butea monosperma, gel, physicochemical properties, in-vitro permeation, stability.


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