Mon, 20 Nov 2017

Nanosponges: Revolution in Nanotechnology

B. Tejeswara Rao*1, V. Saikishore1, D. Gowtham Kumar1, A. Prameela Rani2

1 Bapatla college of pharmacy, Bapatla, Guntur 522101, Andhra Pradesh, India.

2 University College of Pharmaceutical Sciences, Acharya Nagarjuna University, Nagarjuna Nagar, Guntur – 522510, Andhra Pradesh, India.


ABSTRACT

Nanosponges are the advancement in nano technology, which are the conspicuous answers for the various formulation challenges like low aqueous solubility, controlled release and targeted release. Nanosponges do not show the bursting release which is the main obstacle in the most of the nano particles formulations. Nanosponges are a novel class of nanoparticles with nanostructured hyper branched polymers and few nanometres wide cavities, in which a large variety of substances can be encapsulated. Nanosponges also have colloidal sizes with a mean diameter of less than 1 μm and narrow size distribution and form opalescent suspensions on dispersion in water. The formulation of nanosponges involves simple chemistry. Nanosponges could be a perfect solution for resolving the scalability issues of various nano approaches in the pharmaceutical industry, paving the way for a nano-revolution.

Keywords: nanosponges, controlled release, targeted release, colloidal sizes.


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