Mon, 20 Nov 2017

In-Vitro Anti-Oxidant Property Evaluation of Different Extract of Artocarpus Chaplasha Bark

Kishower Shams 1, Abdullah Al Mamun 1, Mohammed Abdullah Jainul 1, Amin Chowdhury 1, Shofiul Azam* 1, Shadman Rahman

1. Department of Pharmacy, International Islamic University Chittagong,154/A, College road, Chittagong, Bangladesh


ABSTRACT

This investigation is made upon the plant Artocarpus chaplasha, the bark of it, to find out its anti-oxidant property. The anti-oxidant property of this plant part was investigated using different solvent for extraction, such as ethanol, ethyl acetate, methanol and chloroform. Different types extract is used to see different extent of result as many phytochemicals are readily extracted in ethanol but not in methanol, and so on. In case of anti-oxidant the scavenging power (IC50) of DPPH radical was 55.15, 163.10, 166.94 and 407.875µg/ml for aforementioned extracts respectively. By the time IC50 ascorbic acid has 47.19µg/ml. There’s also test for total phenolic and flavonoid content was carried out and the ressult for each was 3.63, 61.97, 2.15 and 3.18mg/gm for each extracts respectively in terms of phenolic content. Total flavonoid content was 116.17, 121.51, 82.33 and 63.67mg/gm for each different extracts respectively.

Keywords: IC50, A. chaplasha, scavenging, reducing power, anti-oxidant


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