Mon, 20 Nov 2017

Microchip: New Approach In Novel Drug Delivery System

Bhagyashree Tulashidas Chothe1*, Prashant Suresh Devmore1, Waghchaure Pravin S1, Battase Anil P1, Patil Piyusha B1.

1.Govindrao Nikam College of pharmacy Sawarde,Tal. - Chiplun, Dist.- Ratnagiri, Maharashtra, India, 415606


ABSTRACT

Now days there is need of using novel drug delivery systems to avoid side effects of conventional drug delivery systems and to achieve more significant effects from drug delivery system. Microchip is a new approach in the novel drug delivery system. It is a device act as an implant and delivers required quantity of drug on the site of action at specific time. This method is beneficial in chronic diseases which having long time therapy. Device has substrate, reservoirs, reservoir cap, microprocessors, battery, antenna, biocompatible coating etc. There are different types to deliver drug from the reservoirs. Diffusion method, electro thermal method, diamond electrophoretic method, electrochemical degradation method, polymer degradation method. By using one of these methods optimum drug can deliver.  This device having so many advantages like it stores the drug for long period of time and also protects the drug. Effective concentration of drug can be maintained in blood for long period of time. This system is more beneficial to treat chronic diseases. Chronic diseases require therapy for long period of time which improves patient non-compliance. Chronic diseases like diabetes, cancer, and osteoporosis can be treated by using microchip.There are some limitations in this type of drug delivery system which can be overcome in future research study. This type of drug delivery system can take new era in the world of medicine and technology.

Keywords-microprocessor, electrophoretic, biocompatible, osteoporosis


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