DOI: 10.21276/ajptr
Fri, 19 Apr 2019

Dubowitz Syndrome- A Review


Sudarshan Ramachandran*1, G. Sree Vijayabala1

1.Department of Oral Medicine and Radiology Sibar Institute of Dental Sciences, Guntur

2.Department of Oral Medicine and Radiology ,Thai Moogambikai Dental College and Hospital, Chennai



Dubowitz syndrome is a genetic and chromosomal instability disorder characterized by growth hormone deficiency or defects in the cholesterol biosynthetic pathway. It is characterized by retarded growth, several craniofacial manifestations, skin eruption, soft-tissue syndactyly, central nervous system and oral manifestations. There are reports of even malignant tumors associated with this syndrome. This manuscript reviews the manifestations and management of the dubowitz syndrome.

Keywords: Dubowitz, Growth deficiency, Malignant 

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