Sat, 18 Nov 2017

Drug Loaded Beads: Current Status

 

Ravindra Kumar Rawal1*, Shubhendra Jha1, P.S. Chauhan1, Atul Kumar1, S.D. Maurya1

1.Department of Pharmacy, IEC Group of Institutions, Knowledge Park - I, Greater Noida, U.P. India


 

ABSTRACT

The aim of writing this review is to put a light on the recent trends in development of Drug loaded Beads. Drug loaded beads are gastro retentive drug delivery systems based on multi Unit approach and are prepared to obtain prolonged or controlled drug delivery, to improve bioavailability, stability and target drug to specific sites. These are Spherical in shape and approximately 1.5 mm in diameter. These can be prepared by various methods like ionotropic gelation, hydrogel embedment, solvent evaporation and Melt Solidification by using different polymers. Promising enhancement in bioavailability and site specificity has been achieved by drug loaded beads.

Keywords: FDDS, Beads, Buoyancy, Polymers


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