Sat, 18 Nov 2017

Effect of Herbal Preparations on Cellular Immunity in Rats

 

Barde AA, Worlikar PS, Bhalsinge RR, Ladukar NO,

1.Department of Pharmacology,Padmashree Dr. D.Y. Patil Medical College, Hospital & Research Centre, Dr. D.Y. Patil Vidyapeeth, Pimpri, Pune-18.


 

ABSTRACT

The present study was planned to evaluate the effect of Sitopaladi churna & a herbal preparation on cell mediated immunity: by haematological parameters & by phagocytic activity of polymorpho nuclear  (PMN) cells in rats. Effect of Sitopaladi churna (1000 mg/ kg), Decoction of  herbs(10 ml/ kg) containing Embelia ribes seeds, Cymbopogon citratus(lemon grass), Zingiber officinale (ginger), Ocimum Sanctum(tulsi) on cell mediated immunity was evaluated by haematological parameters and by studying phagocytic activity by PMN cells. Both & herbal preparations shown increased cellular immunity as compared to control. Both herbal preparations shown comparable results with Septilin syrup (marketed by Himalaya) which was used as positive control (P>0.05). The study demonstrates that herbal preparations used in this study trigger cell mediated  immunity.

Keywords: Cell mediated immunity, Herbal preparations, Haematological parameters, Sitopaladi churna, Phagocytic activity

 


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