DOI: 10.21276/ajptr
Fri, 19 Apr 2019

Effect of Herbal Preparations on Cellular Immunity in Rats


Barde AA, Worlikar PS, Bhalsinge RR, Ladukar NO,

1.Department of Pharmacology,Padmashree Dr. D.Y. Patil Medical College, Hospital & Research Centre, Dr. D.Y. Patil Vidyapeeth, Pimpri, Pune-18.



The present study was planned to evaluate the effect of Sitopaladi churna & a herbal preparation on cell mediated immunity: by haematological parameters & by phagocytic activity of polymorpho nuclear  (PMN) cells in rats. Effect of Sitopaladi churna (1000 mg/ kg), Decoction of  herbs(10 ml/ kg) containing Embelia ribes seeds, Cymbopogon citratus(lemon grass), Zingiber officinale (ginger), Ocimum Sanctum(tulsi) on cell mediated immunity was evaluated by haematological parameters and by studying phagocytic activity by PMN cells. Both & herbal preparations shown increased cellular immunity as compared to control. Both herbal preparations shown comparable results with Septilin syrup (marketed by Himalaya) which was used as positive control (P>0.05). The study demonstrates that herbal preparations used in this study trigger cell mediated  immunity.

Keywords: Cell mediated immunity, Herbal preparations, Haematological parameters, Sitopaladi churna, Phagocytic activity


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