Sat, 18 Nov 2017

Effect of various Membranes and their Thickness on Osmotic Tablet of Lornoxicam.

 

 

 

Sameer Sheaikh1*, H. Kalinkar2, A. Chandewar2

1. Prist University, Thanjavur(T.N)

2. P. Wadhwani college of pharmacy, Yavatmal


 

ABSTRACT

Osmotic systems use the principle of osmosis as delivery force to deliver the drug from the system, and the release rate is unaffected by the body’s pH and other physiological and gastrointestinal factors. Osmotic tablet of lornoxicam is prepared successfully to deliver drug in controlled release form for once day therapy in arthritis by overcoming all the side effect and enhancing bioavailability. The objective of the present work was to design osmotically driven oral drug delivery system containing Lornoxicam as an active ingredient and evaluate the effect of various membranes( microporous and semipermiable) on release of drug from osmotic tablet. Core tablet of lornoxicam is prepared, coated with cellulose acetate (39.8 D.S.) in which batch 6b (semipermiable) give the maximum of 91.04% release from osmotic tablet of lornoxicam in control passion as compare to other(microporous membrane coated batches.

Keywords: Osmotic tablet, Lornoxicam, NSAID’s, oral osmotic table, cellulose acetate.


[PDF]  Viewed: 882  Downloaded: 126
  • Call for paper

    American Journal of PharmTech Research (AJPTR) is a peer-reviewed, bimonthly official international journal allowing access to abstracts and full-text.

    Read more...

     

  • Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.

    Read more...

  • Article Statastics

    American Journal of PharmTech Research (AJPTR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission

    American Journal of PharmTech Research (AJPTR) is one of the International open access journal devoted to various disciplines in science and technology.

    Read more...

web counter
web counter