Mon, 20 Nov 2017

A Review on Orally Disintegrating Tablets:Innovations and Advances

Achuth Reddy Vookanti*1, AnnaBalaji2, M.S.Uma Shankar3, Kranthi Rao Poladi4.

1. Department of Pharmaceutics, Trinity College of Pharmaceutical Sciences, Satavahana University, Peddapalli, Karimnagar-505172. Andhra Pradesh, India.


ABSTRACT

The Rapid growing area for the last few decades in the pharmaceutical industry, are the Oral Disintegrating Tablets. They effortlessly dissolve or disintegrate in saliva within 60 seconds. Here, disintegration plays a critical role, disintegrants or superdisintegrants in the dosage forms are included for advancement of solid orals. The Excipients used in the formulation of ODT’s allow quick release of the drug, with faster dissolution. The innovations in the platform of formulating ODTs are aimed at both increasing the performance of the dosage form by decreasing the disintegration time and increasing the patient compliance. These achievements require constant promotion of formulation variables as well as techniques in the production of dosage forms. An attempt is made by this article to divulge the strategies which are used by inventors for improving the performance and acceptability of ODTs.

Keywords: Zydis Technology, Orasolv Technology, Super Disintegrants, Fast Dissolving.


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