Mon, 20 Nov 2017

Phytochemical and Pharmacological Studies of Bryophyllum daigremontianum (Raym.)

Shazid M. Sharker1, Md. Khalid Hossain1, Mohammad R. Haque1, A. N. M. Hamidul Kabir2, Choudhury M. Hasan1, Mohammad A. Rashid*1

1.Phytochemical Research Laboratory, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh

2. Department of Applied Chemistry & Chemical Engineering, Faculty of Engineering, University of Dhaka, Dhaka-1000, Bangladesh


ABSTRACT

A total of 4 compounds have been isolated from a methanol extract of Bryophyllum daigremontianum. These compounds were identified as glut-5(6)-en-3β-ol (1), mixture of α-amyrin (2a) & β-amyrin (2b) and stigmasterol (3), by extensive analysis of NMR data and by comparison with published values. The crude extract was subjected to assay for antioxidant potential through determination of total phenolic content, membrane stabilizing and thrombolytic activities, which revealed potent antioxidant and moderate membrane stabilizing activities and inhibition of clot of rat’s blood.

Keywords: Bryophyllum daigremontianum, glutenol, α- & β-amyrin, stigmasterol, antioxidant, phenolics.


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