DOI: 10.21276/ajptr
Tue, 25 Jun 2019

Antibacterial Studies of Transition Metal Complexes of Tetradentate Thiazole Based Schiff Base

S. Priya1, J. Senthil Kumaran1, N. Jayachandramani1 and S. Mahalakshmi1*

1.PG & Research Department of Chemistry, Pachaiyappa’s college, Chennai 600 030, India.


A novel Schiff base ligand and its metal complexes of Co(II), Ni(II), Cu(II) and Zn(II)  were synthesized and characterized. The characterization was done by using elemental analyses, molar conductivity, magnetic susceptibility, Mass, 1H NMR, 13C NMR, UV-Vis and IR spectroscopy. The experimental data predict that all the complexes are mononuclear with M(II) being coordinated by a tetradentate Schiff base ligand through the deprotonated oxygen atom, nitrogen atom in thiazole ring and two azomethine nitrogen atoms. The data confirm that the complexes have the composition of [ML] Cl type. The electronic absorption spectral data of the complexes propose a square planar geometry around the central metal ion. The biological activities of the synthesized compounds were tested against bacteria by well-diffusion method.

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