Tue, 21 Nov 2017

Novelanti-Psoriatic topical herbal gel containing cassiatora seeds extract

Patel Ruchi *1, Chandur Viresh1, Makadiya Punit1, AR Shabaraya1

1.Department of Pharmaceutics*1, Srinivas college of Pharmacy, Valachil Mangalore-574143


ABSTRACT

Herbal medicine has become an integral part of standard healthcare based on combination of traditional usage and on-going scientific research. Gel is a semisolid system consisting of dispersion made up of either small inorganic particles or large organic molecules enclosing an interpenetrated liquid. The inorganic particles form a three dimensional structure. The gel formulation was designed by using ethanolic extract of Cassia tora seeds and evaluated for various physiological measurements; preparation involved various concentration combinations of Carbopol 934 and Sodium CMC. Containing 1.55%of Cassia tora extract, Glycerin, Methyl paraben, Propyl paraben and required amount of distilled water and neutralized by drop wise addition of tri-ethanolamine to get gel like consistency. The results of physiochemical parameters of formulations were pH (6.8 to 6.89), viscosity, spreadability, extrudability, in-vitro release respectively. Concentration and combination effect of Carbopol 934 and Sodium CMC showed increased consistency and sustained action with increase in concentration.

Keywords: Herbal gel, Cassia tora, Carbopol 934, Sodium CMC


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