DOI: 10.21276/ajptr
Mon, 25 Mar 2019

In-Vitro In-Vivo Correlation Studies - An overview

P. Ramasubramaniyan1*, Shibin raj1, N. Venkateshan1, S. Palanichamy1, L. Subramanian1, P. Solairaj1

1.Sankaralingam Bhuvaneswari College of Pharmacy, Sivakasi-626130.


In vitro-invivo correlation plays a key role in pharmaceutical development of dosage form, optimization of formulation. This articles describes about the regulatory criteria and the factors associated with developing an In-vitro and in-vivo correlation. This factors plays an important role in optimizing the design and protocol required fort development of any dosage form and to identify the bioavailability pattern of the dosage forms. This article provide information on the various guidelines, factors in developing the correlations, bio pharmaceutical classification system,and other applications.

Keywords: In Vitro In Vivo correlation, Food and Drug Administrations Factors, Bio pharmaceutical classification system.


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