DOI: 10.21276/ajptr
Sun, 21 Jul 2019

A cross sectional study (prevalence rate (%)) on antibiotic drug sensitivity pattern in gram-negative and gram-positive uropathogens in tertiary care hospital in India

Karisetty Basappa1*, Mangala Lahkar1, Anjana Devee2,

1. Department of Pharmacy Practice, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam-781032.

2. Asso.professor, Department Of Medicine, Gauhati Medical College & Hospital, Guwahati – Assam.


An organism is called “susceptible” to a drug when the infection caused by it is likely to act in response to treatment with this drug, at the suggested dosage. There are many bacterial species, including E.coli are showing an increasing resistance to antibiotics and E.coli is an important pathogen of urinary tract. The growing Prevelance of antimicrobial resistance is a most important health problem and is linked with high morbidity and mortality. Antimicrobial susceptibility pattern of gram negative was observed towards Nitrofurantoin (55.38%) followed by Cotrimaxazole (22.96%), amikacin (25.93) and Ceftriaxone (12.85%) in case of E.coli and Klebsiella. Enterococcus shown maximum sensitivity to linezolid (89.11%) followed by Nitrofurantoin (51.69%), but ofloxicin (9.7%), Imipenem (9.41%) and Amikacin shown very low sensivity. So, the decision on selection of antibiotic therapy should be made in discussion with microbiologist and pharmacist.

Keywords:Antibiotic sensitivity, prevalence rate, E.coli, Staphylococcus, monitoring of antibiotics.

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