Mon, 20 Nov 2017

Synthesis and Evaluation of New N-GlucosylatedIsothiobiurets as Antimicrobial Agents

Raksha S. Bokade*1, Gajanan V. Korpe1

1. P.G. Department of Chemistry, ShriShivaji College, Akola - 444001, India


ABSTRACT

Several 1-Tetra-O-acetyl-β-D-glucopyranosyl-5-aryl-isothiobiurets were synthesized by the interaction of tetra-O-acetyl-β-D-glucopyranosylthiocarbamides with various aryl isocyanatesand were evaluated for their antibacterial and antifungal activities. The identities of these new N-glucosides have been established on the basis of elemental analysis, IR, 1HNMR, 13CNMR and MS spectral studies.

Keywords: Glucopyranosylthiocarbamides, GlucosylIsothiobiurets, Synthesis, Antimicrobial Activity.


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