Mon, 20 Nov 2017

Synthesis and In-Vitro Analysis of Azetidinone Derivatives as Anthelmintic and Anti-Bacterial Agents

Ambareen Shaikh1*, Jyotsna Meshram1, Bhavna Kandpal1

1. Department of Chemistry, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur-440033, Maharashtra, India.


ABSTRACT

Herein, a series of azetidinone derivatives incorporating dihydropyrimidinone moiety 4(a-h) were prepared. The structures of newly synthesized compounds were confirmed on the basis of elemental analysis, FTIR and 1H NMR spectroscopy. The synthesized compounds were evaluated for their anthelmintic and anti-bacterial activity and it was found that the compounds were pharmacological active and gave appreciable results.

Keywords: Azetidinone derivative; anthelmintic; anti-bacterial.


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