Mon, 18 Dec 2017

Polyherbal Maceration Methanolic Extraction for Nootropic Activity

J.Anantha Lakshmi*1, D. Satyavati2

1. Sri Venkateswara College of Pharmacy,Madhapur. Hyderabad.

2. Sri Datta College of Pharmacy, Ibrahimapatnam. Hyderabad.


ABSTRACT

Nootropic drugs used as a memory enhancer can improve thinking, memory, and alertness in people with Alzheimer’s disease and other disease that affect the mind. Memory is perhaps the most vital of all aspects that differentiates human beings from other animals. However, memory can become faulty due to several reasons, and in that case the person is not able to make full use of his or her potentials. Since ages, drugs and natural remedies have been prescribed to enhance memories in people. 4 million people are thought to be suffering from age related memory and increased risk of developing Alzheimer’s disease. The present study investigate the nootropic activity of poly herbal methanolic extraction (Rhodiola Rodantha Root, Blepharis Maedeterpensis Root, Celastrus Paniculatus Plant seed, Brassica Caulorapa  Bud) by using Active avoidance paradigm, Passive avoidance paradigm, Scopolamine-induced amnesia,  Sodium nitrite intoxication method to assess the nootropic activity.

Keywords: Nootropic activity, Alzheimer’s disease, RhodiolaRodantha, Blepharis Maedeterpensis, Celastrus Paniculatus, Brassica Caulorapa


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