DOI: 10.21276/ajptr
Thu, 23 May 2019

Synthesis, Characterization and Biological Activities of Some Novel Heterocyclic Chalcone Derivatives

M Yaseen Mowlana1*, A Jamal Abdul Nasser1, R Karthikeyan1

1. PG & Research Department of Chemistry, Jamal Mohamed College, Thiruchirappalli -20.


Chalcones are a category of compounds consisting of two aryl rings linked by an α,β-unsaturated ketone moiety. The synthesized compounds CEA and CMA were evaluated for antimicrobial activity by disc diffusion method. The antibacterial and antifungal activity was evaluated against Moraxella, Enterobacter, Pseudomonas aeruginosa (bacterial strains), Candida albicans, A.niger and Trichophyton (fungal strains) using Erythromycin (for bacteria) and Ciprofloxacin (for fungi) as the standard drugs. The structure of synthesized compounds has been elucidated by IR, 1H, 13C NMR and elemental analysis.

Keywords: Chalcone, antibacterial, antifungal, Nystatin and ciprofloxacin.

[PDF]   Viewed: 993   Downloaded: 127
  • Call for paper

    American Journal of PharmTech Research (AJPTR) is a peer-reviewed, bimonthly official international journal allowing access to abstracts and full-text.



  • Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.


  • Article Statastics

    American Journal of PharmTech Research (AJPTR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission

    American Journal of PharmTech Research (AJPTR) is one of the International open access journal devoted to various disciplines in science and technology.


web counter
web counter