DOI: 10.21276/ajptr
Fri, 22 Mar 2019

Hepatitis B immunity status of Biomedical Students in Usmanu Danfodiyo University Sokoto, North Western Nigeria.

Okwesili AN1, Hassan Jafaru 1, Erhabor O1*, Abdulrhaman Y 1, Uko EK 2, Udomah F 3.

1. Faculty of Medical Laboratory Science, Department of Haematology and Blood Transfusion Science, Usmanu Danfodiyo University Sokoto, Nigeria.

2. Department of Haematology, University of Calabar Nigeria.

3. Department of Haematology, University of Calabar Teaching Hospital, Calabar, Nigeria.


The aim of this study was to investigate the Hepatitis B immunity status of Biomedical Students of Usmanu Danfodiyo University Sokoto, North-Western Nigeria. CTK Biotech (USA) Onsite HBsAb ELISA kit was used for the determination of HBsAb status of subjects. We investigated the HBsAb status of 186 biomedical students aged ≥ 18 years (mean age 26 ± 2.0 years) made up of 147 males and 39 females. Out of 186 subject analyzed, 69 (37.1%) were Medical, 75(40.3%) were Medical Laboratory Science and 42(22.6%) were Nursing students. Age group distribution among these subject shows that majority 108(58.0%) were in the 21-25 years age group. Subjects were stratified based on marital status. Majority of subjects were single 173(93.1%) compared to married 13 (6.9%). Ethnic distribution of subjects indicated that 104(55.9%) were Hausa, 32 (17.2%) were Yoruba while 20(10.8%), 9(4.8%) and 21(11.3%) were Fulani, Igbo and other ethnic groups respectively. Among the 186 subjects studied, only 13(7.0%) has had prior complete course of hepatitis B vaccination (p=0.001). Protective HBsAb titre (>10miu/ml) was evident in 72(38.7%) of the subjects while 114 (61.3%) did not had no protective HBsAb titre (<10miu/ml) (p=0.01). Among the biomedical students who have had a previous complete course of hepatitis B vaccination, a significant proportion 61.5% have protective titres (<10) while only 38.5% had protective vaccination. The result of this current study has shown that the prevalence of protective hepatitis B titres and the rate of vaccination uptake are low among Biomedical Science Students in Sokoto, Nigeria. There is a high incidence of needle stick injury. We recommend that all students entering into the Biomedical professions be screened for hepatitis B and that those who are negative and have no protective HBsAb status be offered full course of protective hepatitis B vaccination prior to commencement of their training.

Keywords: Hepatitis B immunity status, Biomedical Students, Usmanu Danfodiyo University, Nigeria.

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