DOI: 10.21276/ajptr
Mon, 20 May 2019

Fast Disintegrating Tablet Containing Cassia Angustifolia (Senna)

V Sai Shivram1, Dalavi Vishal1*, Mandavkar Yuvaraj1, Deshmukh Swapnil1

1. Research & Development, Tulip Lab. Pvt.,Ltd.-Ranjangaon, Pune, India.


Cassia angustifolia is popularly known as senna, since its leaves and pods are common laxatives, they are widely used in medicine and as a household remedy for constipation all over the world popularly in Europe and US. It is available in various dosage forms such as tablets, capsules, granules, liquids and in combination with other laxatives. The objective of the present research work is to develop a preservative free formulation with direct compression approach, complying to USP dissolution test, microbiological purity and standards of heavy metals laid down by WHO. The tablets prepared by direct compression approach are economical, have minimum processing steps, faster disintegration, rapid onset of action and complying to all other tablets parameters.

Keywords: Heavy metal, microbial count, preservative free, senna extract, USP dissolution.

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