Sat, 16 Dec 2017

Floating with Bioadhesion:A Unique Expansion in Gastroretetive Drug Delivery System

Shaikh Siraj*1, Molvi K.I. 1, G. J Khan1, Shaoor Ahmad1, Shaikh Mohsin1, Shaikh Salman1

1. Ali-Allana College of pharmacy, Akkalkuwa  dist Nandurbar  (MH), India


ABSTRACT

Gastro retentive drug delivery system is benefited system in which dosage form retained in stomach prolong period of time and drug release long period of time. Floating system means that float over the surface of the gastric contents when the stomach is full but at the time stomach is empties and the tablet reaches the pylorus the buoyancy of the dosage may be decrease & bioadhesive system becomes dislodged from the stomach wall when the system is full but a floating -bioadhesive system would overcome these drawback of floating and bioadhesive system and improving the therapeutic effect of the drug involved.   So this Floating-bioadhesive dosage forms exhibit a unique combination of floatation and adhesion for prolonged residence in the Stomach. Currently this floating bioadhesive approach is not only used for tablets but also for microsphere, beads & other dosage forms. This review article focus on recently used combination approaches to deliver drug by gastrointestinal drug delivery like Bioadhesive and floating.

Keywords: Oral drug delivery, floating with bioadhesive, Gastric residence time, Polymers etc.


[PDF]  Viewed: 417  Downloaded: 119
  • Call for paper

    American Journal of PharmTech Research (AJPTR) is a peer-reviewed, bimonthly official international journal allowing access to abstracts and full-text.

    Read more...

     

  • Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.

    Read more...

  • Article Statastics

    American Journal of PharmTech Research (AJPTR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission

    American Journal of PharmTech Research (AJPTR) is one of the International open access journal devoted to various disciplines in science and technology.

    Read more...

web counter
web counter