Sat, 16 Dec 2017

Antihistaminic Activity of Herbal Drug Isolated from Cuscuta reflexa Roxb. Growing in Kashmir Valley

Firdous A Mala1*, Mushtaq A Sofi1, Fayaz A Lone 1

1. Govt. Degree College Handwara J&K, India.193221.


ABSTRACT

The aim of present study was to find out the herbal drug which has potential antihistaminic properties. The ethanolic extract of cuscuta reflexa Roxb was found quite useful in showing anti histaminic activities, when tested on experimental albino rats. The rats were divided into four groups of two animals each. Group I was served as control and received water with ad-libitum but not treated and sacrificed for the observation of mast cells which were found 15.50± 2% intact and 88.20±2 % disrupted. In the II group which was treated with ethanolic extract of Cuscuta reflexa, it was noticed that when the dose of 50 mg/kg body weight were given orally with water ,the disruption of mast cells were found 35.60±2 % disrupted and intact mast cells were found 64.40±2 %. In the III group dose of 100 mg/kg body weight, the disruption of mast cells were found 27.70±2 % and intact mast cells were found 72.30±2 %. The rats of group IV received 10mg/kg of prednisolone (reference drug) orally for 4 days.

Keywords: Mast cell stabilization, Cuscuta reflexa, Phytochemical, Antihistaminic, Asthma.


[PDF]  Viewed: 350  Downloaded: 83
  • Call for paper

    American Journal of PharmTech Research (AJPTR) is a peer-reviewed, bimonthly official international journal allowing access to abstracts and full-text.

    Read more...

     

  • Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.

    Read more...

  • Article Statastics

    American Journal of PharmTech Research (AJPTR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission

    American Journal of PharmTech Research (AJPTR) is one of the International open access journal devoted to various disciplines in science and technology.

    Read more...

web counter
web counter