Sat, 16 Dec 2017

Studies on the Role of Escherichia coli in Pregnancy Related Miscarriages (Spontaneous Abortions) In Upland Area of Rivers State of Nigeria

Okoroiwu .GI1*, Wachukwu  CK2

1. School of Health Sciences; National  Open University of Nigeria (noun), 14/16 Ahmadu Bello way, Victoria island Lagos, Nigeria.

2. Department of Medical Laboratory Science. Rivers state University of Science and Technology. Port Harcourt, Rivers State.


ABSTRACT

Escherichia coli infection is a serious health threat to the ordinary people, especially the intending mothers all over the world, but more so in the developing countries.  In this cohort study, 300 Endocervical swabs(ECS) and mid-stream urine(MSU) samples  were collected within 8hours to 24hours of miscarriages to determine the prevalence and  role of Escherichia coli in pregnancy related miscarriages in the Upland Area of Rivers state, in this era of frequent miscarriages amongst Women. The ECS were cultured on chocolate, blood  and MacConkey agar while MSU samples were inoculated on MacConkey and CLED media respectively. The growths were isolated and characterized using biochemical activities including fermentation, Gram reaction, motility, colonial appearance, media selection . ECS were also screened for Chlamydia trachomatis using Chlamydia Rapid Test Device kit . Of the 130 isolates , 54(41.5%) of them were Escherichia coli while the proportions of the infected women were highest within the 18-20 years and 21-25years age cohorts(P<0.05). The prevalence of Escherichia coli showed significant relationship (p<0.05) with the illiteracy level of the women, more so, the level of this result statistically (p<0.05) associates Escherichia coli with miscarriages in the area and this calls for mass literacy and awareness among the intending mothers.

Keywords: Miscarriage, Escherichia coli, Endocervical smear, Urine, Upland


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