DOI: 10.21276/ajptr
Wed, 17 Oct 2018

Method Development and Validation of Forced Degradation Studies of Montelukast Sodium by Using UV Spectroscopy

Sk Mastanamma1*, P.Saidulu1, G.Rambabu1, I.S.Tejaswini1

1. Department pharmaceutical analysis, Acharya Nagarjuna university-522510, Guntur, Andhra Pradesh, India.


A new, rapid, precise, selective and sensitive validative forced degradative UV spectroscopy method was developed for estimation of Montelukast sodium in bulk and pharmaceutical formulation in the developed method, the absorbance was measured at  272.19nm.the drugs obeyed the Beer’s law in the  concentration range of 30-150μg/mL. Accuracy studies of the method were determined by recovery studies and were found to be 99.9 for Montelukast sodium. It can be used for routine analysis of drug in bulk and in pharmaceutical formulation.

Keywords: forced degradation studies, Montelukast sodium,validation.

[PDF]   Viewed: 1369   Downloaded: 167
  • Call for paper

    American Journal of PharmTech Research (AJPTR) is a peer-reviewed, bimonthly official international journal allowing access to abstracts and full-text.



  • Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.


  • Article Statastics

    American Journal of PharmTech Research (AJPTR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission

    American Journal of PharmTech Research (AJPTR) is one of the International open access journal devoted to various disciplines in science and technology.


web counter
web counter