Thu, 23 Nov 2017

Curcumin: The Golden Spice In The Treatment of Rheumatoid Arthritis

Anusha Raj1, Afrasim Moin2, D V Gowda*1, Rakesh Hiremath1, Chetan G. Shinde1, Atul Srivastava1 and Riyaz Ali M. Osmani1

1.Department of Pharmaceutics, JSS University, JSS College of Pharmacy, SS Nagara, Mysore -570015, Karnataka, India

2.Department of Pharmaceutics, College of Pharmacy, University of Hail, Hail-81442, Saudi Arabia


ABSTRACT

Curcumin, an orange-yellow colored component of turmeric is a diarylheptanoid. It is the principal curcuminoid obtained from the rhizomes of the Curcuma longa plant (Zingiberaceae). It is a polyphenol product obtained from turmeric. It is been used in some medicinal preparation and even as a food-coloring agent. By the in vivo and in vitro studies it is confirmed that curcumin has antiviral, anti-arthritic anticancer, anti-amyloid, anti-inflammatory and antioxidant properties. The present article highlights the role of curcumin in the treatment of rheumatoid arthritis (RA). It emphasizes on the oral, transdermal and parenteral routes of drug delivery systems and the emerging trends related to these delivery systems such as solid dispersions, cyclodextrin inclusion compounds, solid lipid nanoparticles, liposomes, micro nano emulsions, transdermal patches, topical gel and proniosomes etc.

Keywords: Rheumatoid arthritis, Curcumin, Drug delivery, Treatment.


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