Thu, 23 Nov 2017

Solid Lipid Nanoparticles- A Breakthrough In Novel Drug Delivery System

Sweety Tom1, D V Gowda*1, Manjunath M2, Tibey Mary Koshy1, Godugu Karunakar1 and Atul Srivastava1

1.Department of Pharmaceutics, JSS College of Pharmacy, JSS University, SS Nagara, Mysore -570015, Karnataka, India

2.Department of Pharmaceutics, Farooquia College of Pharmacy, Tilak Nagara, Mysore -570001, Karnataka, India


ABSTRACT

Solid lipid nanoparticles (SLNs) are the superseding drug delivery system in the nanotechnology sphere. SLNs has been developed at the beginning of 1990s with potential applications in the field of pharmaceuticals, cosmeceuticals, clinical medicine along with research as a substitute to the traditional colloidal carrier systems such as emulsions, liposomes since they exclude those downsides of the traditional system. SLN s offers a great way for controlled drug delivery and site targeting drug delivery as well. This article gives general information about the solid lipid nanoparticles, their production procedures and characterization. In addition to that, the recent advancements of drug delivery systems using SLNs were reviewed.

Keywords: Solid lipid nanoparticles, colloidal carriers, drug delivery.


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