Thu, 23 Nov 2017

Evaluation of Antipyretic Activity of Methanolic Leaf Extract of Barleria Prionitis In Albino Rats

Lincy Joseph *1, Mathew George 2, Pushpa Brijwal 3,Rajimol T Chandran1.

1.Department of Pharmaceutical Chemistry, Pushpagiri College of pharmacy, Thiruvalla - 689107, Kerala

2. Department of Pharmacology, Pushpagiri College of pharmacy, Thiruvalla - 689107, Kerala

3.Department of Pharmacognosy, School of Pharmaceutical Scioences, Jaipur National University, Jaipur-302025


ABSTRACT

Leaves of Barleria prionitis (family- Acanthaceae) are used in traditional medicines for various ailments. The present study is to investigate the antipyretic activity of methanolic extract of Barleria prionitis in Albino rats. Brewer’s yeast induced pyrexia method was selected for evaluation. The standard drug used was paracetamol (150 mg/kg/p.o). Neck and Rectal temperature were recorded by digital thermometer and compared with the control group. Based on the results obtained, the methanolic leaf extract of Barleria prionitis showed significant antipyretic activity.

Keywords: Barleria prionitis; Antipyretic activity; Brewer’s yeast induced pyrexia method.


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