Wed, 22 Nov 2017

Knoevenagel Condensation of Aldehydes with Meldrum’s Acid in Presence of Phenyl boronic acid as a catalyst

Vishvanath D. Patil1*, Ketan P. Patil1, Nagesh R. Sutar1, Avinash.T.Gatade1.

1.Organic Chemistry Research Laboratory, Department of Chemistry, C.K.Thakur A.C.S. College, New Panvel, Raigad, Maharashtra, India.


ABSTRACT

The Knoevenagel condensation of Meldrum’s acid with aromatic aldehydes proceeded efficiently at room temperature in the presence of catalytic amounts of Phenyl boronic acid. This approach offers many advantages such as good product yields, short reaction yield, easy isolation of products.

Keywords: Active methylene compounds, Knoevenagel condensation, Meldrum’s acid, Phenyl boronic acid, Room temperature.


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