Wed, 22 Nov 2017

Evaluation of Anti-Arthritic Activity of Roots of Asparagus Racemosus

Suvarna laxmi Kodumuru1*, A. Srinivas Rao1, N.V.B.L.A. Baby Kambampati1

1.Department of Pharmacology, Bhaskar pharmacy college, Yenkapally village, Moinabad, Rangareddy-501504.


ABSTRACT

A. Racemosus; Aqueous Extract; Paw volume; Erythrocyte sedimentation rate (ESR). Asparagus Racemosus (Linn) popularly called as Challan gadda belongs to Asparagaceae family. Phytochemical constituents such as Steroidal saponins, glycosides, Oligospirostanoside, Isoflavones, Furan compounds and Flavonoids have been reported in  A. Racemosus. In the present study the roots of Asparagus Racemosus were studied for anti arthritic activity The antiarthritis activity was evaluated by using FCA induced arthritis model in Wistar rats. The assessment made during 32 days showed that. The parameters evaluated in this study are Body weight, Paw volume, White blood cell count (WBC),Red blood cell count (RBC),Hemoglobin count (Hb), Erythrocyte sedimentation rate (ESR). The statistical data indicated that the Aqueous Extract of Asparagus racemosus root (200mg/kg) and (400mg/kg) was administered 1 hr before the administration of Freund’s Complete - Adjuvant (0.1ml. subplanetar region). ***P <0.05 and ***P <0.005 significant compared to control group respectively. The experimental data demonstrated that A. Racemosus displayed remarkable antiarthritic activity.

Keywords: Antiarthritic activity, Aqueous Extract, A. Racemosus


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