Tue, 21 Nov 2017

Approaches and advances in transdermal delivery of insulin -A Review

Jigyasa vindru1, Aravind Ram AS2, D. V. Gowda1*, Avinash S1, Hamsika M, and Atul Srivastava1

1.Dept. of Pharmaceutics, JSS University, JSS College of Pharmacy, SS Nagara, Mysore -570015, Karnataka, India

2.Department of Pharmaceutics, Farooqia College of Pharmacy, Tilak Nagara, Mysore-570001, Karnataka, India


ABSTRACT

Even today the most preferred delivery of drugs is still through oral route but because of some inherited limitations with this route, various other routes have been explored including transdermal. Delivery and complete absorption of the drugs is the major concern these days due to various reasons including poor solubility and incomplete bioavailability, this could be due to incomplete presystemic absorption or presystemic degradation. Transdermal drug delivery system is the method by which the drug absorption occurs through the skin primarily for its systemic effect. It provides better therapeutic efficacy and safety for the administration of insulin. Most of the oral anti-diabetic drug exhibit low bioavailability and hence a poor patient compliance. Hence, it can be used as better site for delivery of numerous drugs including proteins and peptides such as insulin.

Keywords: Insulin; transdermal delivery; antidiabetic drugs; bioavailability

 


[PDF]  Viewed: 458  Downloaded: 133
  • Call for paper

    American Journal of PharmTech Research (AJPTR) is a peer-reviewed, bimonthly official international journal allowing access to abstracts and full-text.

    Read more...

     

  • Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.

    Read more...

  • Article Statastics

    American Journal of PharmTech Research (AJPTR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission

    American Journal of PharmTech Research (AJPTR) is one of the International open access journal devoted to various disciplines in science and technology.

    Read more...

web counter
web counter