DOI: 10.21276/ajptr
Mon, 27 May 2019

A Review On Isatin and Its Pharmacological Profile

Rekha Pharswan*1, Meenu Chaudhary1

1. Department of Pharmaceutical Science, Shri Guru Ram Rai Institute of Technology & Science, Patelnagar, Dehradun.


Isatin is an endogeneous and an important class of heterocyclic compound. It possess indole nucleus having both keto and lactam moiety with a diverse pharmacological properties like antimicrobial, antitubercular, anticonvulsant activity etc. Isatin derivatives are synthetically important substrates, which can be used for the synthesis of a large variety of heterocyclic compounds, and as raw material for drug synthesis. Recently, isatin derivatives have attracted strong interest in organic and medicinal chemistry due to their potent biological and pharmacological activities. The purpose of this review is to provide information on the pharmacological activities of isatin and its derivative.

Keywords: Isatin, Antimicrobial, Anticonvulsant, Anticancer, Antitubercular, Anti-inflammatory.

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